

| 카탈로그 번호 | MA332014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse DAND5 Polyclonal Antibody (MA332014) is a rabbit polyclonal antibody detecting DAND5 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse DAND5 (Ser55-Leu185). | ||||||||
| 타겟 | DAN domain family member 5 (Cerberus-like protein 2) (Cerl-2) | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q76LW6 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | DAN domain family member 5 (DAND5) is a ~19 kDa protein. Antagonist of the extracellular signaling protein NODAL, which is required for correct left-right patterning during embryonic development. Antagonist of BMP4 signaling. Antagonist of TGF-beta signaling. Independently of its role in left-right axis establishment, plays a role during heart development, possibly through the regulation of TGF-beta/Nodal signaling pathway. Displays anti-angiogenic activity by inhibiting endothelial sprouting, migration, and proliferation. 1. Marques, S. et al. (2004) Genes & development 18, 2342-7. PMID: 15466485 2. Araújo, AC. et al. (2014) PloS one 9, e102716. PMID: 25033293 3. Popovic, N. et al. (2021) EMBO molecular medicine 13, e12005. PMID: 33587337 | ||||||||
| 참고사항 | For research use only. |

Lane 1: MCF-7 cell lysate


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