

| 카탈로그 번호 | MF844014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse DGAT1 Polyclonal Antibody (MF844014) is a rabbit polyclonal antibody detecting DGAT1. Suitable for Mouse and Rat.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse DGAT1 (Gly2-Ser92). | ||||||||
| 타겟 | ACAT-related gene product 1, AGRP1, ARAT, Acyl-CoA retinol O-fatty-acyltransferase, DGAT, DGAT1, Diacylglycerol O-acyltransferase 1, Diglyceride acyltransferase, EC:2.3.1.20, EC:2.3.1.76, Retinol O-fatty-acyltransferase | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9Z2A7 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Diacylglycerol O-acyltransferase 1 (DGAT1) is a ~56 kDa protein. Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Highly expressed in epithelial cells of the small intestine and its activity is essential for the absorption of dietary fats. In liver, plays a role in esterifying exogenous fatty acids to glycerol, and is required to synthesize fat for storage. Also present in female mammary glands, where it produces fat in the milk. May be involved in VLDL (very low density lipoprotein) assembly. 1. Yen, CL. et al. (2005) Journal of lipid research 46, 1502-11. PMID: 15834126 2. Shih, MY. et al. (2009) The Journal of biological chemistry 284, 4292-9. PMID: 19028692 3. McFie, PJ. et al. (2010) The Journal of biological chemistry 285, 37377-87. PMID: 20876538 4. Qi, J. et al. (2012) Journal of lipid research 53, 1106-16. PMID: 22493088 5. Ma, Z. et al. (2017) Journal of lipid research 58, 1091-1099. PMID: 28420705 6. Buhman, KK. et al. (2002) The Journal of biological chemistry 277, 25474-9. PMID: 11959864 | ||||||||
| 참고사항 | For research use only |
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