Anti-Mouse EFNA1 Polyclonal Antibody (MB164014)

Name: Anti-Mouse EFNA1 Polyclonal Antibody
Brand: abinScience
SKU: MB164014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MB164014

설명

Anti-Mouse EFNA1 Polyclonal Antibody (MB164014) is a rabbit polyclonal antibody detecting EFNA1 in ELISA, IHC, WB. Suitable for Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse EFNA1 (Met1-Ser182).

타겟

Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) [Cleaved into: Ephrin-A1, secreted form]

정제

Purified by antigen affinity column.

등록번호

P52793

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ephrin-A1 (EFNA1) is a ~23 kDa protein. Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Involved in angiogenesis, regulating vascular endothelial cell differentiation and migration through activation of EPHA2. Acts as a ligand for EPHA3, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development. May also contribute to dendritic spine morphogenesis.

1. Hunter, SG. et al. (2006) Molecular and cellular biology 26, 4830-42. PMID: 16782872

2. Fang, WB. et al. (2008) The Journal of biological chemistry 283, 16017-26. PMID: 18387945

3. Frieden, LA. et al. (2010) Developmental dynamics : an official publication of the American Association of Anatomists 239, 3226-34. PMID: 20960543

4. Fu, WY. et al. (2007) Nature neuroscience 10, 67-76. PMID: 17143272

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Mouse EFNA1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse EFNA1 Polyclonal Antibody (MB164014)

개요

이미지

참고 문헌

데이터시트

SDS