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Anti-Mouse FGA Polyclonal Antibody (MF809014)

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개요
카탈로그 번호MF809014
설명
Anti-Mouse FGA Polyclonal Antibody (MF809014) is a rabbit polyclonal antibody detecting Fga. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Mouse FGA (Thr552-Gln789).
타겟 Fga, Fibrinogen alpha chain, Fibrinopeptide A
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 E9PV24
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
배경

Fibrinogen alpha chain (FGA) is a ~87 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.

1. Suh, TT. et al. (1995) Genes & development 9, 2020-33. PMID: 7649481
2. Drew, AF. et al. (2001) Blood 97, 3691-8. PMID: 11389004
3. Ni, H. et al. (2000) The Journal of clinical investigation 106, 385-92. PMID: 10930441
4. Yang, H. et al. (2009) Blood 114, 425-36. PMID: 19332769
5. Johnson, LL. et al. (2003) The Journal of experimental medicine 197, 801-6. PMID: 12629066
6. Luo, D. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 4149-61. PMID: 23487423
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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