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| 카탈로그 번호 | MW632013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Mouse | ||||
| 응용 분야 | ELISA, FCM | ||||
| 숙주 종 | mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | BAK209B11 | ||||
| 타겟 | IL-13, IL13, Interleukin-13, NC30 | ||||
| 내독소 수준 | < 10 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P20109 | ||||
| RRID | Anti-Mouse IL13 Antibody (BAK209B11) (abinScience Cat# MW632013, RRID:AB_3725661) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Interleukin-13 (IL13) is a ~14 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B. 1. Finkelman, FD. et al. (2004) Immunological reviews 201, 139-55. PMID: 15361238 2. Zhang, M. et al. (2021) Journal of immunology (Baltimore, Md. : 1950) 207, 3070-3080. PMID: 34789557 3. Mayer, JU. et al. (2021) Nature immunology 22, 1538-1550. PMID: 34795444 4. Takeda, K. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 3220-2. PMID: 8871614 5. Duffen, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1347-1359. PMID: 29305434 | ||||
| 참고사항 | For research use only. |
Detects Mouse IL13 in indirect ELISAs.
SDS-PAGE for Anti-Mouse IL13 Antibody (BAK209B11).
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