

| 카탈로그 번호 | MV121014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse IL-31RA Polyclonal Antibody (MV121014) is a rabbit polyclonal antibody detecting IL-31RA in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse IL31RA (Val19-Glu210). | ||||||||
| 타겟 | Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (GLM-R) (mGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (Novel cytokine receptor 10) (NR10) (ZcytoR17) | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8K5B1 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Interleukin-31 receptor subunit alpha (IL31RA) is a ~80 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. 1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896 2. Cevikbas, F. et al. (2014) The Journal of allergy and clinical immunology 133, 448-60. PMID: 24373353 3. Broxmeyer, HE. et al. (2007) Experimental hematology 35, 78-86. PMID: 17379091 | ||||||||
| 참고사항 | For research use only. |
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