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Anti-Mouse IL-9 Polyclonal Antibody (MB771014)

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개요
카탈로그 번호MB771014
설명
Anti-Mouse IL9 Polyclonal Antibody (MB771014) is a rabbit polyclonal antibody detecting Il9. Suitable for Mouse.
종 반응성Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Mouse IL9 (Gln19-Pro144).
타겟 Cytokine P40, IL-9, Il9, Interleukin-9, T-cell growth factor P40
내독소 수준 Please contact with the lab for this information.
순도 >95% as determined by SDS-PAGE.
정제 Purified by antigen affinity column.
등록번호 P15247
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
배경

Interleukin-9 (IL9) is a ~16 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs.

1. Townsend, JM. et al. (2000) Immunity 13, 573-83. PMID: 11070175
2. Elyaman, W. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 12885-90. PMID: 19433802
3. Khan, WI. et al. (2003) Infection and immunity 71, 2430-8. PMID: 12704113
4. Druez, C. et al. (1990) Journal of immunology (Baltimore, Md. : 1950) 145, 2494-9. PMID: 2145361
5. Kimura, Y. et al. (1995) International immunology 7, 115-20. PMID: 7718508
6. Demoulin, JB. et al. (1999) The Journal of biological chemistry 274, 25855-61. PMID: 10464327
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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