Mouse IL9 Recombinant Protein (N-His) (MB771012)

Name: Mouse IL9 Recombinant Protein (N-His)
Brand: abinScience
SKU: MB771012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MB771012
Description	Recombinant Mouse IL9 Protein, N-His (MB771012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P15247
Protein length	Gln19-Pro144
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Cytokine P40, IL-9, Il9, Interleukin-9, T-cell growth factor P40
Background	Interleukin-9 is a ~16 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. 1. Townsend, JM. et al. (2000) Immunity 13, 573-83. PMID: 11070175 2. Elyaman, W. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 12885-90. PMID: 19433802 3. Khan, WI. et al. (2003) Infection and immunity 71, 2430-8. PMID: 12704113 4. Druez, C. et al. (1990) Journal of immunology (Baltimore, Md. : 1950) 145, 2494-9. PMID: 2145361 5. Kimura, Y. et al. (1995) International immunology 7, 115-20. PMID: 7718508 6. Demoulin, JB. et al. (1999) The Journal of biological chemistry 274, 25855-61. PMID: 10464327
Note	For research use only

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SDS-PAGE for Recombinant Mouse IL9 Protein, N-His

References

Datasheet

Mouse IL9 Recombinant Protein (N-His).pdf

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Formula

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Mouse IL9 Recombinant Protein (N-His) (MB771012)

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