Anti-Mouse JAM3 Polyclonal Antibody (MP669014)

Name: Anti-Mouse JAM3 Polyclonal Antibody
Brand: abinScience
SKU: MP669014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

MP669014

설명

Anti-Mouse JAM3 Polyclonal Antibody (MP669014) is a rabbit polyclonal antibody detecting JAM3 in ELISA, IHC, WB. Suitable for Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse JAM3 (Glu30-Asp239).

타겟

Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]

정제

Purified by antigen affinity column.

등록번호

Q9D8B7

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Junctional adhesion molecule C (JAM3) is a ~34 kDa protein. Junctional adhesion protein that mediates heterotypic cell-cell interactions with its cognate receptor JAM2 to regulate different cellular processes. Plays a role in homing and mobilization of hematopoietic stem and progenitor cells within the bone marrow. At the surface of bone marrow stromal cells, it contributes to the retention of the hematopoietic stem and progenitor cells expressing JAM3. Plays a central role in leukocytes extravasation by facilitating transmigration through the endothelium. Plays a role in spermatogenesis where JAM2 and JAM3, which are respectively expressed by Sertoli and germ cells, mediate an interaction between both cell types and play an essential role in the anchorage of germ cells onto Sertoli cells and the assembly of cell polarity complexes during spermatid differentiation.

1. Gliki, G. et al. (2004) Nature 431, 320-4. PMID: 15372036

2. Lamagna, C. et al. (2005) Molecular biology of the cell 16, 4992-5003. PMID: 16093349

3. Arcangeli, ML. et al. (2014) Stem cells (Dayton, Ohio) 32, 1043-54. PMID: 24357068

4. Ludwig, RJ. et al. (2005) The Journal of investigative dermatology 125, 969-76. PMID: 16297198

5. Lamagna, C. et al. (2005) Cancer research 65, 5703-10. PMID: 15994945

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Mouse JAM3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse JAM3 Polyclonal Antibody (MP669014)

개요

이미지

참고 문헌

데이터시트

SDS