中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | MB123207 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Mouse | ||||
| 응용 분야 | Blocking, ELISA, FCM | ||||
| 숙주 종 | Rat | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, kappa | ||||
| 클론 ID | CX5 | ||||
| 타겟 | NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d | ||||
| 내독소 수준 | <1 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 관련 제품 | pH 7.4 Dilution Buffer | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | O54709 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF. | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Mouse NKG2D Antibody (CX5)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
