

| 카탈로그 번호 | MY340014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse PTHLH Polyclonal Antibody (MY340014) is a rabbit polyclonal antibody detecting PTHLH. Suitable for Mouse and Rat.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse PTHLH (Lys35-His175). | ||||||||
| 타겟 | Osteostatin, PLP, PTH-rP, PTHLH, PTHRP, PTHrP, PTHrP[1-36], PTHrP[107-139], PTHrP[38-94], Parathyroid hormone-like protein, Parathyroid hormone-related protein | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P22858 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Parathyroid hormone-related protein (PTHLH) is a ~20 kDa protein. Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. 1. Karaplis, AC. et al. (1994) Genes & development 8, 277-89. PMID: 8314082 2. Lee, K. et al. (1996) Endocrinology 137, 5109-18. PMID: 8895385 3. Guo, J. et al. (2010) Endocrinology 151, 3502-13. PMID: 20501677 4. Hens, JR. et al. (2007) Development (Cambridge, England) 134, 1221-30. PMID: 17301089 | ||||||||
| 참고사항 | For research use only |
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