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| 카탈로그 번호 | HY413014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-MPO Polyclonal Antibody (HY413014) is a rabbit polyclonal antibody detecting MPO in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MPO (Val165-Gly278). | ||||||||
| 타겟 | Myeloperoxidase, MPO | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P05164 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Myeloperoxidase (MPO) is a ~83 kDa protein. Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage. 1. Furtmüller, PG. et al. (1998) Biochemistry 37, 17923-30. PMID: 9922160 2. Cederlund, M. et al. (2015) Frontiers in physiology 6, 11. PMID: 25698971 | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-MPO polyclonal antibody at 1ug/mL on various samples.
Lane 1: HL-60 cell lysate
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