Anti-MSN Polyclonal Antibody (HB033014)

Name: Anti-MSN Polyclonal Antibody
Brand: abinScience
SKU: HB033014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HB033014

설명

Anti-MSN Polyclonal Antibody (HB033014) is a rabbit polyclonal antibody detecting MSN in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human MSN (Ile354-Met577).

타겟

Membrane-organizing extension spike protein, MSN, Moesin

정제

Purified by antigen affinity column.

등록번호

P26038

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Moesin (MSN) is a ~67 kDa protein. Ezrin-radixin-moesin (ERM) family protein that connects the actin cytoskeleton to the plasma membrane and thereby regulates the structure and function of specific domains of the cell cortex. Tethers actin filaments by oscillating between a resting and an activated state providing transient interactions between moesin and the actin cytoskeleton. Once phosphorylated on its C-terminal threonine, moesin is activated leading to interaction with F-actin and cytoskeletal rearrangement. These rearrangements regulate many cellular processes, including cell shape determination, membrane transport, and signal transduction. The role of moesin is particularly important in immunity acting on both T and B-cells homeostasis and self-tolerance, regulating lymphocyte egress from lymphoid organs.

1. Huang, L. et al. (1999) The Journal of biological chemistry 274, 12803-10. PMID: 10212266

2. Urzainqui, A. et al. (2002) Immunity 17, 401-12. PMID: 12387735

3. Iontcheva, I. et al. (2004) Infection and immunity 72, 2312-20. PMID: 15039356

4. Serrador, JM. et al. (1997) The Journal of cell biology 138, 1409-23. PMID: 9298994

5. Serrador, JM. et al. (1998) Blood 91, 4632-44. PMID: 9616160

6. Lagresle-Peyrou, C. et al. (2016) The Journal of allergy and clinical immunology 138, 1681-1689.e8. PMID: 27405666

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-MSN Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-MSN Polyclonal Antibody (HB033014)

개요

이미지

참고 문헌

데이터시트

SDS

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