

| 카탈로그 번호 | VK011034 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Murine minute virus/MVM NS1 Polyclonal Antibody (VK011034) is a rabbit polyclonal antibody detecting NS1 in ELISA, IHC, WB. Suitable for Murine minute virus and Parvovirus LuIII.
Highlights
|
||||||||
| 종 반응성 | Murine minute virus (MVM) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Murine minute virus NS1 (Tyr6-Thr253). | ||||||||
| 타겟 | NS1 | ||||||||
| 순도 | >90% | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P03134 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||||
| 제품 사용 정보 |
| ||||||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | Initiator protein NS1, NS1, EC:3.1.21.-, EC:3.6.4.12, NCVP1, Non-capsid protein NS-1, Non-structural protein NS1, NS1 | ||||||||
| 배경 | Initiator protein NS1 is a ~76 kDa protein. Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication. Also plays a role in viral packaging and transactivation of several promoters. Binds site-specifically to 2-3 approximate tandem copies of the tetranucleotide 5'TGGT3' within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR). Cooperatively binds Ori with host PIF and probably other host factors, which activate the nickase function of NS1. Becomes covalently attached to the 5' end of the nick and provides a 3'OH for priming DNA synthesis. 1. Christensen, J. et al. (2002) Journal of virology 76, 6518-31. PMID: 12050365 2. Christensen, J. et al. (1995) Journal of virology 69, 5422-30. PMID: 7636987 3. Cotmore, SF. et al. (2007) Journal of virology 81, 13015-27. PMID: 17898054 4. Willwand, K. et al. (1997) The Journal of general virology 78 ( Pt 10), 2647-55. PMID: 9349487 5. Christensen, J. et al. (2001) Journal of virology 75, 7009-17. PMID: 11435581 | ||||||||
| 참고사항 | For research use only. |
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206

中文
English
한국어
日本語
Español
Français
Русский