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| 카탈로그 번호 | JN891033 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Neisseria meningitidis | ||||
| 응용 분야 | ELISA, SPR | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, kappa | ||||
| 클론 ID | 5H2 | ||||
| 타겟 | nhba, gna2132, Heparin binding protein, Neisserial heparin binding antigen, Genome-derived neisserial antigen 2132, Putative lipoprotein GNA2132, NHBA | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9JPP1 | ||||
| RRID | Anti-Neisseria meningitidis NHBA/Dextranase Antibody (5H2) (abinScience Cat# JN891033, RRID:AB_3727794) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Neisserial heparin binding antigen (NHBA/Dextranase) is a ~44 kDa protein. A major human immunogenic protein detected in patients recovering from meningitidis, where it induces bactericidal antibodies. Binds human cells, heparin and heparan sulfate proteoglycan in vitro via the Arg-rich motif. Heparin-binding to this protein protects bacteria against killing by bactericidal antibodies (serum killing). The bacteria binds a number of human extracellular sialyated and/or sulfated glycans via this protein, including chondroitin sulfate, heparin and ganglioside GT3. Binds DNA non-specifically. 1. Maritan, M. et al. (2018) PloS one 13, e0201922. PMID: 30133484 | ||||
| 참고사항 | For research use only. |
Detects Neisseria meningitidis NHBA/Dextranase in indirect ELISAs.
SDS-PAGE for Anti-Neisseria meningitidis NHBA/Dextranase Antibody (5H2).
Western blot analysis was performed using anti-Neisseria meningitidis NHBA/Dextranase monoclonal antibody at 1µg/ml on various samples.
Lane 1: recombinant Neisseria meningitidis NHBA (Catalog No: JN891012)
Lane 2: negative control
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