Anti-p21/CDKN1A Polyclonal Antibody (HW549014)

Name: Anti-p21/CDKN1A Polyclonal Antibody
Brand: abinScience
SKU: HW549014
Price: 168 USD
Availability: InStock

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100ug

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HW549014

설명

Anti-p21/CDKN1A Polyclonal Antibody (HW549014) is a rabbit polyclonal antibody detecting CDKN1A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CDKN1A (Met1-Pro164).

타겟

CDKN1, MDA-6, Cyclin-dependent kinase inhibitor 1, CIP1, WAF1, CDKN1A, p21, PIC1, Melanoma differentiation-associated protein 6, MDA6, SDI1, CDK-interacting protein 1, CAP20

정제

Purified by antigen affinity column.

등록번호

P38936

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Cyclin-dependent kinase inhibitor 1 (p21/CDKN1A) is a ~18 kDa protein. Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. Involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Also involved in p53-independent DNA damage-induced G2 arrest mediated by CREB3L1 in astrocytes and osteoblasts. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1.

1. LaBaer, J. et al. (1997) Genes & development 11, 847-62. PMID: 9106657

2. Ducoux, M. et al. (2001) The Journal of biological chemistry 276, 49258-66. PMID: 11595739

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-p21/CDKN1A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-p21/CDKN1A Polyclonal Antibody (HW549014)

개요

이미지

참고 문헌

데이터시트

SDS