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Anti-SERPINE1/PAI-1 Polyclonal Antibody (HY185014)

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개요
카탈로그 번호HY185014
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human SERPINE1/PAI-1 (Gly21-Pro402).
타겟 PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1
정제 Purified by antigen affinity column.
등록번호 P05121
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Plasminogen activator inhibitor 1 (SERPINE1/PAI-1) is a ~45 kDa protein. Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.

1. Szabo, R. et al. (2005) The Biochemical journal 390, 231-42. PMID: 15853774
2. Jankun, J. et al. (2007) International journal of molecular medicine 20, 683-7. PMID: 17912461
3. Lee, MH. et al. (1993) Blood 81, 2357-62. PMID: 8481516
4. Fay, WP. et al. (1997) Blood 90, 204-8. PMID: 9207454
5. Anisuzzaman et al. (2011) Biochemical and biophysical research communications 413, 599-604. PMID: 21925150
6. Planus, E. et al. (1997) Journal of cell science 110 ( Pt 9), 1091-8. PMID: 9175705
7. Degryse, B. et al. (2004) The Journal of biological chemistry 279, 22595-604. PMID: 15001579
8. Kjøller, L. et al. (1997) Experimental cell research 232, 420-9. PMID: 9168821
9. Providence, KM. et al. (2008) Archives of dermatological research 300, 303-10. PMID: 18386027
10. Kortlever, RM. et al. (2006) Nature cell biology 8, 877-84. PMID: 16862142
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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