Anti-SFN Polyclonal Antibody (HB182014)

Name: Anti-SFN Polyclonal Antibody
Brand: abinScience
SKU: HB182014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HB182014

설명

Anti-SFN Polyclonal Antibody (HB182014) is a rabbit polyclonal antibody detecting SFN in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SFN (Met1-Ser248).

타겟

Stratifin, Epithelial cell marker protein 1, HME1, 14-3-3 protein sigma, SFN

정제

Purified by antigen affinity column.

등록번호

P31947

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

14-3-3 protein sigma (SFN) is a ~27 kDa protein. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention of GBP1 GTPase by binding to phosphorylated GBP1, thereby inhibiting the innate immune response. Also acts as a TP53/p53-regulated inhibitor of G2/M progression.

1. Wilker, EW. et al. (2005) The Journal of biological chemistry 280, 18891-8. PMID: 15731107

2. Rose, R. et al. (2012) Journal of structural biology 180, 65-72. PMID: 22634725

3. Stevers, LM. et al. (2017) The Biochemical journal 474, 1273-1287. PMID: 28202711

4. Fisch, D. et al. (2023) Science (New York, N.Y.) 382, eadg2253. PMID: 37797010

7. Rietscher, K. et al. (2018) Journal of cell science 131. PMID: 29678907

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-SFN Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-SFN Polyclonal Antibody (HB182014)

개요

이미지

참고 문헌

데이터시트

SDS