Anti-SNRPD1 Polyclonal Antibody (HX906014)

Name: Anti-SNRPD1 Polyclonal Antibody
Brand: abinScience
SKU: HX906014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HX906014

설명

Anti-SNRPD1 Polyclonal Antibody (HX906014) is a rabbit polyclonal antibody detecting SNRPD1 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SNRPD1 (Met1-Arg119).

타겟

Sm-D1, Small nuclear ribonucleoprotein Sm D1, SNRPD1, Sm-D autoantigen, snRNP core protein D1

정제

Purified by antigen affinity column.

등록번호

P62314

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Small nuclear ribonucleoprotein Sm D1 (SNRPD1) is a ~13 kDa protein. Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.

1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638

2. Chari, A. et al. (2008) Cell 135, 497-509. PMID: 18984161

3. Pomeranz Krummel, DA. et al. (2009) Nature 458, 475-80. PMID: 19325628

4. Grimm, C. et al. (2013) Molecular cell 49, 692-703. PMID: 23333303

5. Kondo, Y. et al. (2015) eLife 4. PMID: 25555158

6. Agafonov, DE. et al. (2016) Science (New York, N.Y.) 351, 1416-20. PMID: 26912367

7. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346

8. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770

9. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166

10. Zhang, Z. et al. (2020) Nature 583, 310-313. PMID: 32494006

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-SNRPD1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-SNRPD1 Polyclonal Antibody (HX906014)

개요

이미지

참고 문헌

데이터시트

SDS