Anti-UBD Polyclonal Antibody (HT365014)

Name: Anti-UBD Polyclonal Antibody
Brand: abinScience
SKU: HT365014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HT365014

설명

Anti-UBD Polyclonal Antibody (HT365014) is a rabbit polyclonal antibody detecting UBD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human UBD (Met1-Gly165).

타겟

Diubiquitin, UBD, Ubiquitin-like protein FAT10, Ubiquitin D, FAT10

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O15205

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ubiquitin D (UBD) is a ~18 kDa protein. Ubiquitin-like protein modifier which can be covalently attached to target proteins and subsequently leads to their degradation by the 26S proteasome, in a NUB1-dependent manner. Conjugation to the target protein is activated by UBA6 via adenylation of its C-terminal glycine. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs).

1. Hipp, MS. et al. (2005) Molecular and cellular biology 25, 3483-91. PMID: 15831455

2. Schmidtke, G. et al. (2006) The Journal of biological chemistry 281, 20045-54. PMID: 16707496

3. Schmidtke, G. et al. (2009) FEBS letters 583, 591-4. PMID: 19166848

4. Chiu, YH. et al. (2007) Molecular cell 27, 1014-23. PMID: 17889673

5. Truongvan, N. et al. (2022) Nature communications 13, 4789. PMID: 35970836

6. Gong, P. et al. (2010) Journal of the American Society of Nephrology : JASN 21, 316-26. PMID: 19959714

7. Ebstein, F. et al. (2009) The international journal of biochemistry & cell biology 41, 1205-15. PMID: 19028597

8. Ren, J. et al. (2006) The Journal of biological chemistry 281, 11413-21. PMID: 16495226

9. Kalveram, B. et al. (2008) Journal of cell science 121, 4079-88. PMID: 19033385

10. Ross, MJ. et al. (2006) Journal of the American Society of Nephrology : JASN 17, 996-1004. PMID: 16495380

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-UBD Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-UBD Polyclonal Antibody (HT365014)

개요

이미지

참고 문헌

데이터시트

SDS

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