Anti-VAPA Polyclonal Antibody (HV508014)

Name: Anti-VAPA Polyclonal Antibody
Brand: abinScience
SKU: HV508014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HV508014

설명

Anti-VAPA Polyclonal Antibody (HV508014) is a rabbit polyclonal antibody detecting VAPA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human VAPA (Met8-Met132).

타겟

33 kDa VAMP-associated protein, VAP-33, VAP33, VAPA, VAMP-associated protein A, VAMP-A, VAP-A, Vesicle-associated membrane protein-associated protein A

정제

Purified by antigen affinity column.

등록번호

Q9P0L0

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Vesicle-associated membrane protein-associated protein A (VAPA) is a ~27 kDa protein. Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. STARD3-VAPA interaction enables cholesterol transfer from the ER to endosomes. Via interaction with WDR44 participates in neosynthesized protein export. In addition, recruited to the plasma membrane through OSBPL3 binding. The OSBPL3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface.

1. Lucken-Ardjomande Häsler, S. et al. (2020) The Journal of cell biology 219. PMID: 32344433

2. Di Mattia, T. et al. (2020) The EMBO journal 39, e104369. PMID: 33124732

3. Weber-Boyvat, M. et al. (2015) Experimental cell research 331, 278-91. PMID: 25447204

4. Lehto, M. et al. (2005) Experimental cell research 310, 445-62. PMID: 16143324

5. Weir, ML. et al. (2001) Biochemical and biophysical research communications 286, 616-21. PMID: 11511104

6. Saita, S. et al. (2009) The Journal of biological chemistry 284, 13766-13777. PMID: 19289470

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-VAPA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-VAPA Polyclonal Antibody (HV508014)

개요

이미지

참고 문헌

데이터시트

SDS