

| 카탈로그 번호 | JN845014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Yellowfever mosquito Aed a 2/AeD7L1 Polyclonal Antibody (JN845014) is a rabbit polyclonal antibody detecting Aed a 2 in ELISA, IHC, WB. Suitable for Aedes aegypti.
Highlights
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| 종 반응성 | Aedes aegypti (Yellowfever mosquito) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Yellowfever mosquito Aed a 2/AeD7L1 (Ser18-Gln321). | ||||||||
| 타겟 | Long form salivary protein D7L1, AeD7, AeD7L1, 37 kDa salivary gland allergen Aed a 2, Protein D7, Aed a 2, D7, D7L1, AAEL006424, Aed a 2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P18153 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Long form salivary protein D7L1 (Aed a 2/AeD7L1) is a ~36 kDa protein. Modulates blood feeding of female mosquitoes on vertebrate species by binding and sequestering different mediators involved in the host response, such as biogenic amines and eicosanoids. Binds serotonin, histamine, leukotriene B4, leukotriene C4, leukotriene D4, leukotriene E4, adrenaline and noradrenaline. Does not bind tryptamine and U-46619, a stable analog of thromboxane A2. Exhibits vasodilating activity. Inhibits agonist-induced platelet aggregation but not blood clotting. 1. Martin-Martin, I. et al. (2021) The FEBS journal 288, 2014-2029. PMID: 32799410 2. Martin-Martin, I. et al. (2023) mBio 14, e0228923. PMID: 37909749 3. Calvo, E. et al. (2006) The Journal of biological chemistry 281, 1935-42. PMID: 16301315 4. Calvo, E. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 3728-33. PMID: 19234127 | ||||||||
| 참고사항 | For research use only. |
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