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| 카탈로그 번호 | VK672818 |
|---|---|
| 설명 |
HEK293T SARS-CoV-2 Envelope small membrane protein (E) Stable Cell Line (VK672818) is a stable cell line expressing SARS-CoV-2 Envelope small membrane protein (E). Engineered for consistent, high-level target expression in research applications.
Highlights
|
| 등록번호 | P0DTC4 |
| 응용 분야 | FCM |
| 숙주 종 | HEK293T |
| 종 | Viral (SARS-CoV-2) |
| 타겟 | SARS-CoV-2 Envelope small membrane protein (E) |
| 특성 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 안정성 및 저장 | Frozen in liquid nitrogen. |
| 사양 | 1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium |
| 배경 | Envelope small membrane protein (SARS-CoV-2 Envelope small membrane protein (E)) is a ~8 kDa protein. Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Regulates the localization of S protein at cis-Golgi, the place of virus budding. May act by slowing down the cell secretory pathway. 1. Boson, B. et al. (2021) The Journal of biological chemistry 296, 100111. PMID: 33229438 2. De Maio, F. et al. (2020) Microbes and infection 22, 592-597. PMID: 32891874 |
Untransfected cells and Transfected cells were tested with qPCR.
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