HEK293T SARS-CoV-2 Nucleoprotein (N) Stable Cell Line (VK805818)

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카탈로그 번호	VK805818
설명	HEK293T SARS-CoV-2 Nucleoprotein (N) Stable Cell Line (VK805818) is a stable cell line expressing SARS-CoV-2 Nucleoprotein (N). Engineered for consistent, high-level target expression in research applications. Highlights ●Stable Expression — Engineered for consistent, high-level target expression.
등록번호	P0DTC9
응용 분야	FCM
숙주 종	HEK293T
종	Viral (SARS-CoV-2)
타겟	SARS-CoV-2 Nucleoprotein (N)
특성	Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
안정성 및 저장	Frozen in liquid nitrogen.
사양	1 vial contains at least 2×10^6 cells in 1 mL Freeze Medium
배경	Nucleoprotein (SARS-CoV-2 Nucleoprotein (N)) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373 2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782 3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661