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| 카탈로그 번호 | MF998109 |
|---|---|
| 설명 |
InVivo Plus Anti-Mouse CD4 Antibody (GK1.5) [GK1.5] (MF998109) is a rat monoclonal antibody detecting T-cell surface glycoprotein CD4 in in vivo CD4+ T cell depletion, FCM, WB. Suitable for Mouse.
Highlights
|
| 종 반응성 | Mouse |
| 응용 분야 | in vivo CD4+ T cell depletion, FCM, WB |
| 숙주 종 | Rat |
| 클론성 | Monoclonal |
| 이소타입 | IgG2b |
| 클론 ID | GK1.5 |
| 타겟 | CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
| 내독소 수준 | < 1 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P06332 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivo Plus Anti-Mouse CD4 Antibody (GK1.5)
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