中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | VK589050 |
|---|---|
| 설명 |
InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) [1C19] (VK589050) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
|
| 종 반응성 | Dengue virus 1 (DENV-1), Dengue virus 2 (DENV-2), Dengue virus 3 (DENV-3), Dengue virus 4 (DENV-4) |
| 응용 분야 | ELISA, Neutralization |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | 1C19 |
| 타겟 | Envelope protein E |
| 내독소 수준 | < 1 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Genome polyprotein (Envelope protein E) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions. 1. Kuhn, RJ. et al. (2002) Cell 108, 717-25. PMID: 11893341 2. Sangiambut, S. et al. (2008) The Journal of general virology 89, 1254-1264. PMID: 18420804 3. Colpitts, TM. et al. (2011) PloS one 6, e24365. PMID: 21909430 4. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
