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| 카탈로그 번호 | HF594010 |
|---|---|
| 설명 |
InVivoMAb Anti-Human ApoC3 Antibody (Iv0249) [Iv0249] (HF594010) is a human monoclonal antibody detecting Apolipoprotein C-III in ELISA, FuncS. Suitable for Human.
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FuncS |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | Iv0249 |
| 타겟 | Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3, APOC3 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P02656 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Apolipoprotein C-III (ApoC3) is a ~10 kDa protein. Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners. 1. Chan, DC. et al. (2008) International journal of clinical practice 62, 799-809. PMID: 18201179 2. Yao, Z. et al. (2012) Current opinion in lipidology 23, 206-212. PMID: 22510806 3. Gangabadage, CS. et al. (2008) The Journal of biological chemistry 283, 17416-27. PMID: 18408013 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
SDS-PAGE for InVivoMAb Anti-Human ApoC3 Antibody (Iv0249).
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