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| 카탈로그 번호 | HF664010 |
|---|---|
| 설명 |
InVivoMAb Anti-Human F12 Antibody (Iv0164) [Iv0164] (HF664010) is a human monoclonal antibody detecting F12 in ELISA, Neutralization, WB. Suitable for Human.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Neutralization, WB |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG4, lambda |
| 클론 ID | Iv0164 |
| 타겟 | F12, HAF, Hageman factor, Beta-factor XIIa part 2, Coagulation factor XII |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P00748 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Coagulation factor XII (F12/Coagulationfactor XII) is a ~67 kDa protein. Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. 1. Naito, K. et al. (1991) The Journal of biological chemistry 266, 7353-8. PMID: 2019570 2. MacQuarrie, JL. et al. (2011) Blood 117, 4134-41. PMID: 21304106 3. Brunnée, T. et al. (1993) Blood 81, 580-6. PMID: 8427954 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107) |
SDS-PAGE for InVivoMAb Anti-Human F12 Antibody (Iv0164).
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