InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7) (MY583010)

Name: InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7)
Brand: abinScience
SKU: MY583010
Price: 370 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

MY583010

설명

InVivoMAb Anti-Mouse IL6R (15A7) [15A7] (MY583010) is a rat monoclonal antibody detecting Interleukin-6 receptor subunit alpha in ELISA, FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, FCM, Functional assay, Research in vivo

숙주 종

Rat

클론성

Monoclonal

이소타입

IgG2b, kappa

클론 ID

15A7

타겟

CD126, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6R, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, Soluble interleukin-6 receptor subunit alpha, gp80, sIL6R

내독소 수준

< 1 EU/mg

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P22272

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Interleukin-6 receptor subunit alpha (IL6R) is a ~51 kDa protein. Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling', the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system.

1. Larsen, JV. et al. (2017) Molecular and cellular biology 37. PMID: 28265003

2. Kang, S. et al. (2019) Immunity 50, 1007-1023. PMID: 30995492

3. Spencer, S. et al. (2019) The Journal of experimental medicine 216, 1986-1998. PMID: 31235509

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Mouse IL6R (15A7)

참고 문헌

데이터시트

InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7) (MY583010)

개요

이미지

참고 문헌

데이터시트

SDS

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