中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | MX892020 |
|---|---|
| 설명 |
InVivoMAb Anti-Mouse SIRPA Antibody (Iv0259) [Iv0259] (MX892020) is a mouse monoclonal antibody detecting Tyrosine-protein phosphatase non-receptor type substrate 1 in ELISA, Neutralization. Suitable for Mouse.
|
| 종 반응성 | Mouse |
| 응용 분야 | ELISA, Neutralization |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | lgG1 (D265A) |
| 클론 ID | Iv0259 |
| 타겟 | BIT, Bit, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172a, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, SIRP, SIRPA, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84 |
| 내독소 수준 | < 1 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P97797 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Tyrosine-protein phosphatase non-receptor type substrate 1 (CD172a/SIRPA) is a ~56 kDa protein. Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. 1. Nakaishi, A. et al. (2008) Journal of molecular biology 375, 650-60. PMID: 18045614 2. Sarute, N. et al. (2019) PLoS biology 17, e3000137. PMID: 30726215 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-Mouse SIRPA Antibody (Iv0259)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
