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| 카탈로그 번호 | VK521060 |
|---|---|
| 설명 |
InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (1H1) [1H1] (VK521060) is a human monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, Neutralization. Suitable for Nipah virus (NiV).
|
| 종 반응성 | Nipah virus (NiV) |
| 응용 분야 | ELISA, Neutralization |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1 |
| 클론 ID | 1H1 |
| 타겟 | Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F, Prefusion Protein |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q9IH63 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Fusion glycoprotein F0 (Prefusion Protein) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
Detects Recombinant Nipah virus/HeV F/Fusion glycoprotein F0 Protein, C-His (Cat No.: VK521011) in indirect ELISA.
SDS-PAGE for InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (1H1).
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