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| 카탈로그 번호 | VK805010 |
|---|---|
| 설명 |
InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) [CR3009] (VK805010) is a human monoclonal antibody detecting Nucleoprotein in ELISA, FCM, IF, Neutralization. Suitable for SARS-CoV-2.
Highlights
|
| 종 반응성 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| 응용 분야 | ELISA, FCM, IF, Neutralization |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | CR3009 |
| 테스트된 응용 분야 | WB |
| 타겟 | Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N Protein, SARS-CoV-2 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 관련 제품 | pH 7.4 Dilution Buffer |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P0DTC9 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Nucleoprotein (NP) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373 2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782 3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
Western blot analysis was performed using anti-nucleoprotein monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011)
Lane 2: negative control
Detects recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011) in indirect ELISA
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