

| 카탈로그 번호 | DB199018 |
|---|---|
| 설명 |
Letolizumab ELISA Kit (DB199018) — Quantitative sandwich ELISA for Letolizumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
|
| 샘플 유형 | Plasma, Serum |
| 민감도 | 0.156 μg/ml |
| 범위 | 0.31-5 μg/mL |
| 등록번호 | P29965 |
| 응용 분야 | ELISA |
| 검출 방법 | Colorimetric |
| 분석 유형 | Quantitative |
| 회수율 | 80-120% |
| 배송 | 2-8 ℃ |
| 안정성 및 저장 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| 사양 | Letolizumab |
| 대체 이름 | BMS-986004, 1450981-87-9 |
| 배경 | CD40 ligand (Letolizumab) is a ~29 kDa protein. Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. 1. Graf, D. et al. (1992) European journal of immunology 22, 3191-4. PMID: 1280226 2. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973 3. Blotta, MH. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 156, 3133-40. PMID: 8617933 4. Mikolajczak, SA. et al. (2004) The Journal of experimental medicine 199, 1025-31. PMID: 15067037 |
| 참고사항 | For Research Use Only. |
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