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Mouse Anti-Human Kappa Chain Monoclonal Antibody, FITC (HB980415)

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개요
카탈로그 번호HB980415
설명
Mouse Anti-Human Kappa Chain Monoclonal Antibody, FITC (HB980415) is a mouse monoclonal antibody detecting Kappa chain in ELISA, IF, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●FITC Conjugated — Ready for direct detection without secondary antibody.
종 반응성Human
응용 분야ELISA, IF, WB
숙주 종Mouse
클론성Monoclonal
이소타입IgG1
접합FITC
면역원 Nature Protein
타겟 Second antibody, Second Ab, Mouse Anti-Human IgG, Kappa Chain Monoclonal Antibody, FITC
내독소 수준 Please contact with the lab for this information.
순도 >90% as determined by SDS-PAGE.
관련 제품 Mouse IgG1 kappa Recombinant Isotype Control Antibody (HyHEL-10), FITC
정제 Protein A/G purified from cell culture supernatant.
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Store at 4°C 12 months.
배경

Immunoglobulin kappa constant (Kappa Chain) is a ~11 kDa protein. Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.

1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268
2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
참고사항 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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참고 문헌
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