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| 카탈로그 번호 | VK643012 |
|---|---|
| 설명 |
Recombinant HHV-5/HCMV UL83 Protein, N-GST (VK643012). Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P06725 |
| 단백질 길이 | Thr297-Tyr510 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Human cytomegalovirus (HCMV) (HHV-5) (Human herpesvirus 5) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | 65 kDa matrix phosphoprotein, 65 kDa phosphoprotein, Phosphoprotein UL83, Tegument protein UL83, UL83, pp65 |
| 배경 | 65 kDa phosphoprotein is a ~62 kDa protein. Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus. Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1. Participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes. 1. Abate, DA. et al. (2004) Journal of virology 78, 10995-1006. PMID: 15452220 2. Biolatti, M. et al. (2018) Journal of virology 92. PMID: 29263269 3. Cox, JB. et al. (2025) Journal of virology 99, e0048125. PMID: 40243337 4. Cristea, IM. et al. (2010) Journal of virology 84, 7803-14. PMID: 20504932 |
| 참고사항 | For research use only |
SDS-PAGE for Recombinant HCMV/HHV-5 pp65/UL83 Protein, N-GST
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