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| 카탈로그 번호 | HV781012 |
|---|---|
| 설명 |
Recombinant Human CD264/TNFRSF10D/TRAIL-R4 Protein, N-His (HV781012) expressed in E. coli, spanning Glu81-His211. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9UBN6 |
| 단백질 길이 | Glu81-His211 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 16.21 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | CD264, DCR2, DcR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRAIL-R4, TRAILR4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D |
| 배경 | Tumor necrosis factor receptor superfamily member 10D is a ~41 kDa protein. Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. 1. Degli-Esposti, MA. et al. (1997) Immunity 7, 813-20. PMID: 9430226 2. Pan, G. et al. (1998) FEBS letters 424, 41-5. PMID: 9537512 3. Marsters, SA. et al. (1997) Current biology : CB 7, 1003-6. PMID: 9382840 |
| 참고사항 | For research use only |
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