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| 카탈로그 번호 | HV137021 |
|---|---|
| 설명 |
Recombinant Human CD85h/LILRA2 Protein, C-Fc (HV137021) expressed in Mammalian Cells. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | Mammalian cells |
| 등록번호 | Q8N149 |
| 단백질 길이 | Met1-Asn449(Ser135Leu) |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 75.75 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | CD85 antigen-like family member H, CD85h, ILT-1, ILT1, Immunoglobulin-like transcript 1, LILRA2, LIR-7, LIR7, Leukocyte immunoglobulin-like receptor 7, Leukocyte immunoglobulin-like receptor subfamily A member 2 |
| 배경 | Leukocyte immunoglobulin-like receptor subfamily A member 2 is a ~52 kDa protein. Part of the innate immune responses against microbial infection. Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic bacteria and fungi, including L.pneumophila, M.hyorhinis, S.pneumoniae, S.aureus and C.albicans. Recognizes epitopes that are in part in the variable region of the immunoglobulin light chains, but requires also the constant region for signaling. Binds to a subset of cleaved IgM, IgG3 and IgG4 molecules, but does not bind cleaved IgA1. Binding of N-terminally truncated immunoglobulins mediates activation of neutrophils. 1. Tedla, N. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 1174-9. PMID: 12529506 2. Hirayasu, K. et al. (2016) Nature microbiology 1, 16054. PMID: 27572839 3. Lu, HK. et al. (2012) PloS one 7, e33478. PMID: 22479404 4. Chen, Y. et al. (2009) Journal of molecular biology 386, 841-53. PMID: 19230061 |
| 참고사항 | For research use only |
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