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| 카탈로그 번호 | HP186022 |
|---|---|
| 설명 |
Recombinant Human CENPJ Protein, N-His (HP186022) expressed in E. coli, spanning Ile1149-Leu1338. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9HC77 |
| 단백질 길이 | Ile1149-Leu1338 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 23.99 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | CENP-J, CENPJ, CPAP, Centromere protein J, Centrosomal P4.1-associated protein, Centrosome assembly and centriole elongation protein, LAG-3-associated protein, LAP, LIP1, LYST-interacting protein 1 |
| 배경 | Centrosomal P4.1-associated protein is a ~153 kDa protein. Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as a microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification. 1. Kleylein-Sohn, J. et al. (2007) Developmental cell 13, 190-202. PMID: 17681131 2. Chang, J. et al. (2010) The EMBO journal 29, 2395-406. PMID: 20531387 3. Hung, LY. et al. (2004) Molecular biology of the cell 15, 2697-706. PMID: 15047868 4. Sharma, A. et al. (2016) Developmental cell 37, 362-376. PMID: 27219064 5. Zheng, X. et al. (2016) Nature communications 7, 11874. PMID: 27306797 6. Tang, CJ. et al. (2011) The EMBO journal 30, 4790-804. PMID: 22020124 7. Chang, CW. et al. (2016) Journal of cell science 129, 2501-13. PMID: 27185865 |
| 참고사항 | For research use only |
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