Human ERCC2 Recombinant Protein (N-His) (HB888022)

Name: Human ERCC2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB888022
Price: 211 USD
Availability: InStock

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100ug
1mg

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개요

카탈로그 번호	HB888022
설명	Recombinant Human ERCC2 Protein, N-His (HB888022) expressed in E. coli, spanning Cys489-Leu760. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	P18074
단백질 길이	Cys489-Leu760
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	33.38 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	BTF2 p80, Basic transcription factor 2 80 kDa subunit, CXPD, DNA 5'-3' helicase XPD, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, EC:5.6.2.3, ERCC2, General transcription and DNA repair factor IIH helicase subunit XPD, TFIIH 80 kDa subunit, TFIIH basal transcription factor complex 80 kDa subunit, TFIIH p80, TFIIH subunit XPD, XPD, XPDC, Xeroderma pigmentosum group D-complementing protein
배경	General transcription and DNA repair factor IIH helicase subunit XPD is a ~86 kDa protein. ATP-dependent 5'-3' DNA helicase. Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, not absolutely essential for minimal transcription in vitro. Required for transcription-coupled nucleotide excision repair (NER) of damaged DNA; recognizes damaged bases. Sequestered in chromatin on UV-damaged DNA. When complexed to CDK-activating kinase (CAK), involved in transcription by RNA polymerase II. 1. Kokic, G. et al. (2019) Nature communications 10, 2885. PMID: 31253769 2. Sung, P. et al. (1993) Nature 365, 852-5. PMID: 8413672 3. Coin, F. et al. (1998) Nature genetics 20, 184-8. PMID: 9771713 4. Tirode, F. et al. (1999) Molecular cell 3, 87-95. PMID: 10024882 5. Coin, F. et al. (2007) Molecular cell 26, 245-56. PMID: 17466626 6. Mathieu, N. et al. (2013) Current biology : CB 23, 204-12. PMID: 23352696 7. Aibara, S. et al. (2021) Nature 594, 124-128. PMID: 33902107
참고사항	For research use only

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Human ERCC2 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

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Human ERCC2 Recombinant Protein (N-His) (HB888022)

개요

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데이터시트

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