Human FKTN Recombinant Protein (N-His) (HD574012)

Name: Human FKTN Recombinant Protein (N-His)
Brand: abinScience
SKU: HD574012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요

카탈로그 번호	HD574012
설명	Recombinant Human FKTN Protein, N-His (HD574012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템	E. coli
등록번호	O75072
단백질 길이	Cys250-Tyr461
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	EC:2.7.8.-, FCMD, FKTN, Fukutin, Fukuyama-type congenital muscular dystrophy protein, Ribitol-5-phosphate transferase, Ribitol-5-phosphate transferase FKTN
배경	Ribitol-5-phosphate transferase FKTN is a ~53 kDa protein. Catalyzes the transfer of a ribitol-phosphate from CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1. Required for normal location of POMGNT1 in Golgi membranes, and for normal POMGNT1 activity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development (Probable). 1. Kanagawa, M. et al. (2016) Cell reports 14, 2209-2223. PMID: 26923585 2. Gerin, I. et al. (2016) Nature communications 7, 11534. PMID: 27194101 3. Nishihara, R. et al. (2018) Biochemical and biophysical research communications 497, 1025-1030. PMID: 29477842 4. Xiong, H. et al. (2006) Biochemical and biophysical research communications 350, 935-41. PMID: 17034757 5. Willer, T. et al. (2014) eLife 3. PMID: 25279699
참고사항	For research use only

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Human FKTN Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human FKTN Recombinant Protein (N-His) (HD574012)

개요

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참고 문헌

데이터시트

SDS

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