Human FURIN Recombinant Protein (N-His) (HY484012)

Name: Human FURIN Recombinant Protein (N-His)
Brand: abinScience
SKU: HY484012
Price: 211 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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사양:

50ug
100ug
1mg

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HY484012
설명	Recombinant Human FURIN Protein, N-His (HY484012) expressed in E. coli, spanning Thr105-Ile221. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	P09958
단백질 길이	Thr105-Ile221
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	15.08 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	FUR, PCSK3, PACE, FURIN, Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, Furin
배경	Furin is a ~86 kDa protein. Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif. Mediates processing of TGFB1, an essential step in TGF-beta-1 activation. Converts through proteolytic cleavage the non-functional Brain natriuretic factor prohormone into its active hormone BNP(1-32). By mediating processing of accessory subunit ATP6AP1/Ac45 of the V-ATPase, regulates the acidification of dense-core secretory granules in islets of Langerhans cells. 1. Anderson, ED. et al. (2002) The Journal of biological chemistry 277, 12879-90. PMID: 11799113 2. Leduc, R. et al. (1992) The Journal of biological chemistry 267, 14304-8. PMID: 1629222 3. Barr, PJ. et al. (1991) DNA and cell biology 10, 319-28. PMID: 1713771 4. Wise, RJ. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 9378-82. PMID: 2251280 5. Dahms, SO. et al. (2014) ACS chemical biology 9, 1113-8. PMID: 24666235 6. Hardes, K. et al. (2015) ChemMedChem 10, 1218-31. PMID: 25974265 7. Takahashi, S. et al. (1995) The Journal of biological chemistry 270, 26565-9. PMID: 7592877 8. Takahashi, S. et al. (1993) Biochemical and biophysical research communications 195, 1019-26. PMID: 7690548 9. Anderson, ED. et al. (1997) The EMBO journal 16, 1508-18. PMID: 9130696 10. Dubois, CM. et al. (1995) The Journal of biological chemistry 270, 10618-24. PMID: 7737999
참고사항	For research use only.