Human IRF1 Recombinant Protein (N-His) (HY164042)

Name: Human IRF1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HY164042
Price: 211 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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사양:

50ug
100ug
1mg

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HY164042
설명	Recombinant Human IRF1 Protein, N-His (HY164042) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
발현 시스템	E. coli
등록번호	P10914
단백질 길이	Met1-Pro114
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	15.63 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	IRF-1, IRF1, Interferon regulatory factor 1
배경	Interferon regulatory factor 1 is a ~36 kDa protein. Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired immune responses through the activation of specific target genes and can act as a transcriptional activator and repressor regulating target genes by binding to an interferon-stimulated response element (ISRE) in their promoters. Has an essentail role in IFNG-dependent immunity to mycobacteria. Competes with the transcriptional repressor ZBED2 for binding to a common consensus sequence in gene promoters. 1. Oshima, S. et al. (2004) Molecular and cellular biology 24, 6298-310. PMID: 15226432 2. Dornan, D. et al. (2004) Molecular and cellular biology 24, 10083-98. PMID: 15509808 3. Su, ZZ. et al. (2007) Journal of cellular physiology 213, 502-10. PMID: 17516545 4. Park, J. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 17028-33. PMID: 17942705 5. Bowie, ML. et al. (2008) Advances in experimental medicine and biology 617, 367-74. PMID: 18497060 6. Huang, Y. et al. (2009) PloS one 4, e5397. PMID: 19404407 7. Gao, J. et al. (2010) Cell death and differentiation 17, 699-709. PMID: 19851330 8. Qi, H. et al. (2012) The Journal of biological chemistry 287, 12622-33. PMID: 22367195 9. Somerville, TDD. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 11471-11482. PMID: 32385160 10. Tanaka, N. et al. (1993) Molecular and cellular biology 13, 4531-8. PMID: 7687740
참고사항	For research use only