Human JMJD6 Recombinant Protein (N-His) (HP634012)

Name: Human JMJD6 Recombinant Protein (N-His)
Brand: abinScience
SKU: HP634012
Price: 211 USD
Availability: InStock

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100ug
1mg

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개요

카탈로그 번호	HP634012
설명	Recombinant Human JMJD6 Protein, N-His (HP634012) expressed in E. coli, spanning Met1-Ser291. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q6NYC1
단백질 길이	Met1-Ser291
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	36.42 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, EC:1.14.11.-, Histone arginine demethylase JMJD6, JMJD6, JmjC domain-containing protein 6, Jumonji domain-containing protein 6, KIAA0585, Lysyl-hydroxylase JMJD6, PSR, PTDSR, Peptide-lysine 5-dioxygenase JMJD6, Phosphatidylserine receptor, Protein PTDSR
배경	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 is a ~46 kDa protein. Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Regulates RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Hydroxylates its own N-terminus, which is required for homooligomerization. Plays a role in the regulation of nucleolar liquid-liquid phase separation (LLPS) by post-translationally modifying LIAT1 at its lysine-rich domain which inhibits LIAT1 nucleolar targeting. 1. Chang, B. et al. (2007) Science (New York, N.Y.) 318, 444-7. PMID: 17947579 2. Mantri, M. et al. (2010) Journal of molecular biology 401, 211-22. PMID: 20684070 3. Hahn, P. et al. (2010) PloS one 5, e13769. PMID: 21060799 4. Han, G. et al. (2012) Journal of cellular biochemistry 113, 1663-70. PMID: 22189873 5. Poulard, C. et al. (2014) PloS one 9, e87982. PMID: 24498420 6. Webby, CJ. et al. (2009) Science (New York, N.Y.) 325, 90-3. PMID: 19574390 7. Hong, X. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 14568-72. PMID: 20679243 8. Konuma, T. et al. (2017) Scientific reports 7, 16272. PMID: 29176719
참고사항	For research use only

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Human JMJD6 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human JMJD6 Recombinant Protein (N-His) (HP634012)

개요

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