Human KCNB1 Recombinant Protein (N-His) (HC581012)

Name: Human KCNB1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC581012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요
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개요

카탈로그 번호	HC581012
설명	Recombinant Human KCNB1/Kv2.1 Protein, N-His (HC581012) expressed in E. coli, spanning Glu19-Val186. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q14721
단백질 길이	Glu19-Val186
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	22.29 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	DRK1, Delayed rectifier potassium channel 1, KCNB1, Potassium voltage-gated channel subfamily B member 1, Voltage-gated potassium channel subunit Kv2.1, h-DRK1
배경	Potassium voltage-gated channel subfamily B member 1 is a ~95 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Plays also a role in the regulation of exocytosis independently of its electrical function. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. 1. Li, XN. et al. (2013) The Journal of pharmacology and experimental therapeutics 344, 407-16. PMID: 23161216 2. Shepard, AR. et al. (1999) The American journal of physiology 277, C412-24. PMID: 10484328 3. Ju, M. et al. (2003) The Journal of biological chemistry 278, 12769-78. PMID: 12560340 4. Ikeda, SR. et al. (1992) Pflugers Archiv : European journal of physiology 422, 201-3. PMID: 1283219 5. Mederos Y Schnitzler, M. et al. (2009) The Journal of biological chemistry 284, 4695-704. PMID: 19074135 6. Bocksteins, E. et al. (2009) The Journal of biological chemistry 284, 31625-34. PMID: 19717558 7. Bocksteins, E. et al. (2014) PloS one 9, e98960. PMID: 24901643 8. Albrecht, B. et al. (1993) Receptors & channels 1, 99-110. PMID: 8081723 9. Sano, Y. et al. (2002) FEBS letters 512, 230-4. PMID: 11852086
참고사항	For research use only

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Human KCNB1 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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Human KCNB1 Recombinant Protein (N-His) (HC581012)

개요

이미지

참고 문헌

데이터시트

SDS

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