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| 카탈로그 번호 | HP302022 |
|---|---|
| 설명 |
Recombinant Human RBM24 Protein, N-GST & C-His (HP302022) expressed in E. coli, spanning Thr11-Lys91. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9BX46 |
| 단백질 길이 | Thr11-Lys91 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 37.06 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | RBM24, RNA-binding motif protein 24, RNA-binding protein 24, RNA-binding region-containing protein 6, RNPC6 |
| 배경 | RNA-binding protein 24 is a ~24 kDa protein. Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. 1. Jin, D. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 1158-67. PMID: 20977548 2. Xu, E. et al. (2014) Molecular cancer research : MCR 12, 359-69. PMID: 24375645 3. Lin, Y. et al. (2018) The international journal of biochemistry & cell biology 94, 10-21. PMID: 29104163 4. Zhang, M. et al. (2018) Cell death and differentiation 25, 1118-1130. PMID: 29358667 5. Zhang, T. et al. (2016) Stem cells (Dayton, Ohio) 34, 1776-89. PMID: 26990106 6. Jiang, Y. et al. (2014) The Journal of biological chemistry 289, 3164-75. PMID: 24356969 |
| 참고사항 | For research use only |
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