Human RICTOR Recombinant Protein (N-His) (HP601022)

Name: Human RICTOR Recombinant Protein (N-His)
Brand: abinScience
SKU: HP601022
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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개요

카탈로그 번호	HP601022
설명	Recombinant Human RICTOR Protein, N-His (HP601022) expressed in E. coli, spanning Arg32-Leu254. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	Q6R327
단백질 길이	Arg32-Leu254
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	27.56 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	AVO3 homolog, KIAA1999, RICTOR, Rapamycin-insensitive companion of mTOR, hAVO3
배경	Rapamycin-insensitive companion of mTOR is a ~192 kDa protein. Component of the mechanistic target of rapamycin complex 2 (mTORC2), which transduces signals from growth factors to pathways involved in proliferation, cytoskeletal organization, lipogenesis and anabolic output. In response to growth factors, mTORC2 phosphorylates and activates AGC protein kinase family members, including AKT (AKT1, AKT2 and AKT3), PKC (PRKCA, PRKCB and PRKCE) and SGK1. In contrast to mTORC1, mTORC2 is nutrient-insensitive. Within the mTORC2 complex, RICTOR probably acts as a molecular adapter. RICTOR is responsible for the FKBP12-rapamycin-insensitivity of mTORC2. 1. Sarbassov, DD. et al. (2004) Current biology : CB 14, 1296-302. PMID: 15268862 2. Sarbassov, DD. et al. (2005) Science (New York, N.Y.) 307, 1098-101. PMID: 15718470 3. Dibble, CC. et al. (2009) Molecular and cellular biology 29, 5657-70. PMID: 19720745 4. Julien, LA. et al. (2010) Molecular and cellular biology 30, 908-21. PMID: 19995915 5. Chen, CH. et al. (2011) Science signaling 4, ra10. PMID: 21343617 6. Scaiola, A. et al. (2020) Science advances 6. PMID: 33158864 7. Zhuang, L. et al. (2022) Cell biology international 46, 1693-1703. PMID: 35904232 8. Yu, Z. et al. (2022) The Journal of biological chemistry 298, 102288. PMID: 35926713 9. Treins, C. et al. (2010) Oncogene 29, 1003-16. PMID: 19935711 10. Jacinto, E. et al. (2004) Nature cell biology 6, 1122-8. PMID: 15467718
참고사항	For research use only

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Human RICTOR Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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Working Solution

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Human RICTOR Recombinant Protein (N-His) (HP601022)

개요

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