Human SETD1A Recombinant Protein (N-His) (HC879012)

Name: Human SETD1A Recombinant Protein (N-His)
Brand: abinScience
SKU: HC879012
Price: 211 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug
1mg

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HC879012
설명	Recombinant Human SETD1A Protein, N-His (HC879012) expressed in E. coli, spanning Val1524-Ser1670. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
발현 시스템	E. coli
등록번호	O15047
단백질 길이	Val1524-Ser1670
응용 분야	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
종	Homo sapiens (Human)
성질	Recombinant
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
예측 분자량	19.25 kDa
형태	Lyophilized
저장 완충액	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
재구성	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
배송	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	EC:2.1.1.364, Histone-lysine N-methyltransferase SETD1A, KIAA0339, KMT2F, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, SET1, SET1A, SETD1A, Set1/Ash2 histone methyltransferase complex subunit SET1, hSET1A
배경	Histone-lysine N-methyltransferase SETD1A is a ~186 kDa protein. Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery, forms H3K4me1, H3K4me2 and H3K4me3 methylation marks at active chromatin sites where transcription and DNA repair take place. Responsible for H3K4me3 enriched promoters and transcriptional programming of inner mass stem cells and neuron progenitors during embryogenesis. Required for H3K4me1 mark at stalled replication forks. Mediates FANCD2-dependent nucleosome remodeling and RAD51 nucleofilaments stabilization at reversed forks, protecting them from nucleolytic degradation. 1. Wysocka, J. et al. (2003) Genes & development 17, 896-911. PMID: 12670868 2. Shinsky, SA. et al. (2015) The Journal of biological chemistry 290, 6361-75. PMID: 25561738 3. Higgs, MR. et al. (2018) Molecular cell 71, 25-41.e6. PMID: 29937342 4. Yu, X. et al. (2019) Neuroscience bulletin 35, 1045-1057. PMID: 31197650 5. Kummeling, J. et al. (2021) Molecular psychiatry 26, 2013-2024. PMID: 32346159 6. Amin, HM. et al. (2023) International journal of molecular sciences 24. PMID: 38003223
참고사항	For research use only

이미지

참고 문헌

데이터시트

Human SETD1A Recombinant Protein (N-His).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Human SETD1A Recombinant Protein (N-His) (HC879012)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기