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| 카탈로그 번호 | HC761012 |
|---|---|
| 설명 |
Recombinant Human SPART Protein, N-His (HC761012) expressed in E. coli, spanning Gly198-Gln336. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q8N0X7 |
| 단백질 길이 | Gly198-Gln336 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 17.87 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | KIAA0610, SPART, SPG20, Spartin, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1 |
| 배경 | Spartin is a ~72 kDa protein. Lipophagy receptor that plays an important role in lipid droplet (LD) turnover in motor neurons. Localizes to LDs and interacts with components of the autophagy machinery, such as MAP1LC3A/C proteins to deliver LDs to autophagosomes for degradation via lipophagy. Lipid transfer protein required for lipid droplet degradation, including by lipophagy. Can bind and transfer all lipid species found in lipid droplets, from phospholipids to triglycerides and sterol esters but the direction of lipid transfer by spartin and its cargos are unknown. May be implicated in endosomal trafficking, or microtubule dynamics, or both. 1. Chung, J. et al. (2023) Nature cell biology 25, 1101-1110. PMID: 37443287 2. Wan, N. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2314093121. PMID: 38190532 3. Renvoisé, B. et al. (2010) Molecular biology of the cell 21, 3293-303. PMID: 20719964 |
| 참고사항 | For research use only |
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