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| 카탈로그 번호 | HP417022 |
|---|---|
| 설명 |
Recombinant Human SPRY4 Protein, N-His (HP417022) expressed in E. coli, spanning Phe156-Phe299. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9C004 |
| 단백질 길이 | Phe156-Phe299 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Homo sapiens (Human) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 18.04 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Protein sprouty homolog 4, SPRY4, Spry-4 |
| 배경 | Protein sprouty homolog 4 is a ~32 kDa protein. Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. Represses integrin-mediated cell spreading via inhibition of TESK1-mediated phosphorylation of cofilin. 1. Leeksma, OC. et al. (2002) European journal of biochemistry 269, 2546-56. PMID: 12027893 2. Sasaki, A. et al. (2003) Nature cell biology 5, 427-32. PMID: 12717443 3. Tsumura, Y. et al. (2005) The Biochemical journal 387, 627-37. PMID: 15584898 |
| 참고사항 | For research use only |
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