Anti-Human SPRY4 Polyclonal Antibody (HP417014)

Name: Anti-Human SPRY4 Polyclonal Antibody
Brand: abinScience
SKU: HP417014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HP417014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SPRY4 (Ser178-Arg270).

Target

Protein sprouty homolog 4, Spry-4, SPRY4

Purification

Purified by antigen affinity column.

Accession

Q9C004

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protein sprouty homolog 4 (SPRY4) is a ~32 kDa protein. Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1. Represses integrin-mediated cell spreading via inhibition of TESK1-mediated phosphorylation of cofilin.

1. Leeksma, OC. et al. (2002) European journal of biochemistry 269, 2546-56. PMID: 12027893

2. Sasaki, A. et al. (2003) Nature cell biology 5, 427-32. PMID: 12717443

3. Tsumura, Y. et al. (2005) The Biochemical journal 387, 627-37. PMID: 15584898

Note

For research use only.

Images

References

Datasheet

Anti-Human SPRY4 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SPRY4 Polyclonal Antibody (HP417014)

Overview

Images

References

Datasheet

SDS

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